![]() elegans) Ethical, legal and societal implications (ELSI)Ĥ The linkage map The map was built by linkage studies in 60 large families with grandparents and large numbers of children, collected by the University of Utah and the Centre d'Étude du Polymorphisme Humain (CEPH), Paris Families were typed with over 5000 polymorphic DNA sequences: 60% were microsatellite repeats (mostly dinucleotide (CA) repeats, also some tri- and tetra-nucleotides). Technology development Model organism genome projects (E. 2 The HGP’s primary aims The main aims of the Human Genome Project (HGP) were to: Construct maps of the genome (genetic and physical) Identify all the genes (now known to be about 30,000) Determine the entire DNA sequence (3,000,000,000 bp)ģ Other aims of HGP As well as the genome sequence, the aims were:
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